Two sample MR report
DMAP1_Alveolar Macrophages against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.2672608 | 1.0936082 | 0.8474108 |
| Weighted median | 3 | 0.0993193 | 0.0287286 | 0.0005459 |
| Inverse variance weighted | 3 | 0.0964181 | 0.0218439 | 0.0000101 |
| Simple mode | 3 | 0.1016745 | 0.0322874 | 0.0877688 |
| Weighted mode | 3 | 0.1016008 | 0.0335076 | 0.0937252 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0051639 | 1 | 0.9427133 |
| Inverse variance weighted | 0.1157972 | 2 | 0.9437456 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.1811845 | 0.5447259 | 0.7955784 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 1.81e-05 | 0 | TRUE | 0.6930466 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
